The fastest way to travel from Athens to Istanbul is by flight, which takes around 300 minutes. If speed and convenience are your priorities, this is the best option. However, prices range from 80 to 350 USD, so it's wise to check the current rates and plan accordingly.
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Cheapest
The cheapest option might be the flight at the lower end of the price range, but check current prices and plan accordingly.
For families
For families seeking comfort, the flight is the most suitable option, though the cost can vary.