The fastest way from Pamukkale to Istanbul is by flight, taking approximately 300 minutes. Ticket prices range from 80 to 350 USD. Keep in mind that prices vary and it's important to check current schedules.
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Cheapest
Although there isn't a cheaper flight option, it's advisable to check prices in advance and look for special deals.
For families
The flight offers convenience and speed, which can suit families with children. It's important to consider the higher cost.