The fastest way to travel from Rize to Istanbul is by flight. The journey takes about 300 minutes, with ticket prices ranging from 80 to 350 USD. Consider the relatively high cost against the convenience and speed of flying.
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Cheapest
If budget is a primary concern, check for current prices and try to find cheaper tickets. However, keep in mind that prices can go up to 350 USD.
For families
For families seeking comfort and speed, flying is the preferred choice. The only consideration is the potential high cost.