The fastest way to travel from Rome to Istanbul is by flight, taking approximately 300 minutes. These flights are available through Trip.com, with prices ranging from 80 to 350 USD. Consider the ticket cost and time saved compared to other options.
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Cheapest
The flight can also be a budget option if you find tickets priced at 80 USD, but you'll need to be flexible with flight times.
For families
For families, the flight offers convenience and efficiency, but it's advisable to check ticket availability in advance and plan for the costs.