Flying from Milan to London takes about 300 minutes and costs between 80 and 350 USD. If efficiency is your priority, a flight is the fastest option. However, be aware that prices can vary depending on providers and market conditions.
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Cheapest
For budget travelers, it's wise to check variable prices and opt for cheaper times, but be aware that prices may fluctuate.
For families
Flying is suitable for families seeking a fast and convenient way to reach London, though cost should be considered.