The fastest way to travel from Rome to London is by flight, taking approximately 300 minutes. If you're looking to save time and effort, this is the option for you. However, be aware of the wide price range that can go up to 350 USD.
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Cheapest
There is insufficient information on a budget option, but it's worth checking for the lowest prices offered by Trip.com.
For families
Flying is also suitable for families seeking comfort and speed in reaching London. However, prices might be high for larger families.